BDBM398895 1-(4-chloro-3-((R)-2- hydroxypropoxy)-1-phenyl- 1H-pyrazol-5-yl)-3-((3S,4R)-4- (3,4-difluorophenyl)-1-(2- methoxyethyl)pyrrolidin-3- yl)urea::US10323022, Example 372

SMILES COCCN1C[C@@H](NC(=O)Nc2c(Cl)c(OC[C@@H](C)O)nn2-c2ccccc2)[C@@H](C1)c1ccc(F)c(F)c1

InChI Key InChIKey=MVPPMVTUGAEDGK-GTCCEBARSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398895   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM398895(1-(4-chloro-3-((R)-2- hydroxypropoxy)-1-phenyl- 1H...)
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent