BDBM399012 1-((3S,4R)-4-(3,4-difluorophenyl)- 1-(2-methoxyethyl)pyrrolidin-3- yl)-3-(3-(5-fluoropyridin-3-yl)-4- methyl-1-phenyl-1H-pyrazol-5- yl)urea::US10323022, Example 489

SMILES COCCN1C[C@@H](NC(=O)Nc2c(C)c(nn2-c2ccccc2)-c2cncc(F)c2)[C@@H](C1)c1ccc(F)c(F)c1

InChI Key InChIKey=VWFHRNJUEZEUBM-JYFHCDHNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 399012   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM399012(1-((3S,4R)-4-(3,4-difluorophenyl)- 1-(2-methoxyeth...)
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent