BDBM400144 (S)-N-(3-chloro-4-fluorophenyl)-6-methyl-7-(2-((3-methyl-1-(methylamino)-1-oxobutan-2-yl)amino)-2-oxoacetyl)-2,3-dihydro-1H-pyrrolizine-5-carboxamide ::US10328053, Compound 128::US10874640, Compound 128::US20230270719, Compound 128

SMILES CNC(=O)[C@@H](NC(=O)C(=O)c1c(C)c(C(=O)Nc2ccc(F)c(Cl)c2)n2CCCc12)C(C)C

InChI Key InChIKey=QHGFTHBOWDIITM-SFHVURJKSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 400144   

TargetSodium/bile acid cotransporter(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM400144((S)-N-(3-chloro-4-fluorophenyl)-6-methyl-7-(2-((3-...)
Affinity DataEC50:  170nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM400144((S)-N-(3-chloro-4-fluorophenyl)-6-methyl-7-(2-((3-...)
Affinity DataEC50:  170nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Gilead Sciences

US Patent
LigandPNGBDBM400144((S)-N-(3-chloro-4-fluorophenyl)-6-methyl-7-(2-((3-...)
Affinity DataEC50:  170nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent