BDBM400608 US10000468, Example 15::US10000468, Example 16

SMILES CC(C)Nc1nc(C(=O)N(C)C)c(nc1N1CCC(CC1)Oc1ccc(F)cc1F)C#N

InChI Key InChIKey=OPTDUMDJBXAGPL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 400608   

TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM400608(US10000468, Example 15 | US10000468, Example 16)
Affinity DataEC50:  1.23E+5nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM400608(US10000468, Example 15 | US10000468, Example 16)
Affinity DataEC50:  3.69E+4nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent