BDBM400722 US10000476, Compound I-81

SMILES COc1ccc(Oc2ccc(cc2)C2(Cn3cccc(C)c3=O)NC(=O)NC2=O)cc1

InChI Key InChIKey=OIALZHXVUINAQK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 400722   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Kaken Pharmaceutical

US Patent
LigandPNGBDBM400722(US10000476, Compound I-81)
Affinity DataIC50: <100nMAssay Description:The TACE inhibition test was carried out by measuring TACE activity in the presence and the absence of the test substance using the thus-obtained TAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent