BDBM400736 US10000476, Compound I-95::US10000476, Compound I-96

SMILES Cc1cccn(CC2(NC(=O)NC2=O)c2cccc(c2)-c2ccccc2)c1=O

InChI Key InChIKey=WRHTWMUPIOCQJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 400736   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Kaken Pharmaceutical

US Patent
LigandPNGBDBM400736(US10000476, Compound I-95 | US10000476, Compound I...)
Affinity DataIC50: <100nMAssay Description:The TACE inhibition test was carried out by measuring TACE activity in the presence and the absence of the test substance using the thus-obtained TAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Kaken Pharmaceutical

US Patent
LigandPNGBDBM400736(US10000476, Compound I-95 | US10000476, Compound I...)
Affinity DataIC50: <100nMAssay Description:The TACE inhibition test was carried out by measuring TACE activity in the presence and the absence of the test substance using the thus-obtained TAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent