BDBM400945 2-Amino-N-{4-[(3S,5R)-3-amino-5-(trifluoromethyl)piperidin-1-yl]pyridin-3-yl}-6-pyrimidin-5-ylfuro[3,2-b]pyridine-3-carboxamide::US10000507, Example 111
SMILES N[C@H]1C[C@H](CN(C1)c1ccncc1NC(=O)c1c(N)oc2cc(cnc12)-c1cncnc1)C(F)(F)F
InChI Key InChIKey=WZHSEVKZCUYEMD-CABCVRRESA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 400945
Affinity DataIC50: <10nMAssay Description:Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...More data for this Ligand-Target Pair