BDBM401004 US10005735, Compound 13

SMILES Sc1cccc2cc(cnc12)C(=O)NCc1ccccn1

InChI Key InChIKey=CJOSQTYTDWWQHB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 401004   

Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
California Institute Of Technology

US Patent
LigandPNGBDBM401004(US10005735, Compound 13)
Affinity DataIC50:  3.90E+3nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAMSH-like protease(Homo sapiens (Human))
California Institute Of Technology

US Patent
LigandPNGBDBM401004(US10005735, Compound 13)
Affinity DataIC50:  1.67E+4nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCOP9 signalosome complex subunit 5(Homo sapiens (Human))
California Institute Of Technology

US Patent
LigandPNGBDBM401004(US10005735, Compound 13)
Affinity DataIC50:  5.67E+4nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent