BDBM401297 US10005756, Compound A68

SMILES O[C@@]1(CCN(C1=O)c1ccc2[nH]c(cc2c1)C(=O)NCCCCNC=O)C(=O)NCc1cc(F)cc(Cl)c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 401297   

TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM401297(US10005756, Compound A68)
Affinity DataIC50:  68nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent