BDBM401507 (S)-6-(1,2-dihydroxyethyl)-2-(4- (2-(1-methyl-1H-pyrazol-5-yl)-4- (trifluoromethyl)phenoxy)phenyl) pyrimidine-4-carboxamide::US10005768, Compound 122

SMILES Cn1nccc1-c1cc(ccc1Oc1ccc(cc1)-c1nc(cc(n1)C(N)=O)[C@H](O)CO)C(F)(F)F

InChI Key InChIKey=UANMGMBFKIXLJG-HXUWFJFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 401507   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM401507((S)-6-(1,2-dihydroxyethyl)-2-(4- (2-(1-methyl-1H-p...)
Affinity DataIC50:  79nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent