BDBM401944 5-[[5-[2-methoxy-4-(4-piperidyl)phenyl]-1H-pyrazol-3-yl]amino]pyridine-2-carbonitrilehydrochloride::US10010547, Example 52::US10973817, Example 52
SMILES COc1cc(ccc1-c1cc(Nc2ccc(nc2)C#N)n[nH]1)C1CCNCC1
InChI Key InChIKey=ZGELPTNONNYXQO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 401944
Affinity DataIC50: 0.460nMAssay Description:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO Required co...More data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Chk-1 Kinase Inhibiting ActivityThe compounds of the invention were tested for activity against Chk-1 kinase using the materials and protocols set ou...More data for this Ligand-Target Pair