BDBM402005 5-[[5-[2-methoxy-4-[(1-methyl-4-piperidyl)oxymethyl]phenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile hydrochloride::US10010547, Example 113

SMILES COc1cc(COC2CCN(C)CC2)ccc1-c1cc(Nc2cnc(cn2)C#N)n[nH]1

InChI Key InChIKey=BHHJNFKYSJQQIG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402005   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Cascadian Therapeutics

US Patent
LigandPNGBDBM402005(5-[[5-[2-methoxy-4-[(1-methyl-4-piperidyl)oxymethy...)
Affinity DataIC50:  0.270nMAssay Description:Chk-1 Kinase Inhibiting ActivityThe compounds of the invention were tested for activity against Chk-1 kinase using the materials and protocols set ou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent