BDBM402007 5-[[5-[4-[(1-isopropyl-4-piperidyl)oxymethyl]-2-methoxy-phenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrilehydrochloride::US10010547, Example 115

SMILES COc1cc(COC2CCN(CC2)C(C)C)ccc1-c1cc(Nc2cnc(cn2)C#N)n[nH]1

InChI Key InChIKey=PAZYKCDJJQILES-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402007   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Cascadian Therapeutics

US Patent
LigandPNGBDBM402007(5-[[5-[4-[(1-isopropyl-4-piperidyl)oxymethyl]-2-me...)
Affinity DataIC50:  0.240nMAssay Description:Chk-1 Kinase Inhibiting ActivityThe compounds of the invention were tested for activity against Chk-1 kinase using the materials and protocols set ou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent