BDBM402055 N-(2-((4,6-dimethylpyrimidin-2- yl)(methyl)amino)ethyl)-2-ethoxy-N- ethylbenzamide::US10011595, B-13

SMILES CCOc1ccccc1C(=O)N(CC)CCN(C)c1nc(C)cc(C)n1

InChI Key InChIKey=JCBRAODYZJUEIE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 402055   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402055(N-(2-((4,6-dimethylpyrimidin-2- yl)(methyl)amino)e...)
Affinity DataIC50:  2.01E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402055(N-(2-((4,6-dimethylpyrimidin-2- yl)(methyl)amino)e...)
Affinity DataIC50:  16nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent