BDBM402208 (9aS or 9aR)-7-[2,6-difluoro-4-(2- phenylethynyl)phenyl]-2-(2- ethoxypyrimidin-5-yl)-9a- methyl-4,9-dihydro-3H- pyrazino[1,2-c]pyrimidine- 1,6,8-trione::US10011607, 39

SMILES CCOc1ncc(cn1)N1CCN2C(=O)N(C(=O)C[C@@]2(C)C1=O)c1c(F)cc(cc1F)C#Cc1ccccc1

InChI Key InChIKey=WVCNOLGBRUPCLT-NDEPHWFRSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402208   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM402208((9aS or 9aR)-7-[2,6-difluoro-4-(2- phenylethynyl)p...)
Affinity DataEC50:  96nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent