BDBM402209 (9aS)-7-[2,6-difluoro-4-(2- phenylethynyl)phenyl]-2-(2- isopropoxypyrimidin-5-yl)- 9a-methyl-4,9-dihydro- 3H-pyrazino[1,2-c]pyrimidine- 1,6,8-trione::US10011607, 40

SMILES CC(C)Oc1ncc(cn1)N1CCN2C(=O)N(C(=O)C[C@@]2(C)C1=O)c1c(F)cc(cc1F)C#Cc1ccccc1

InChI Key InChIKey=OPEYJKNEIWCKSP-LJAQVGFWSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402209   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM402209((9aS)-7-[2,6-difluoro-4-(2- phenylethynyl)phenyl]-...)
Affinity DataEC50:  113nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent