BDBM402213 (9aS)-2-[2-(cyclopro- poxy)pyrimidin- 5-yl]-7-[2,6-difluoro-4-(2- phenylethynyl)phenyl]-9a- methyl-4,9-dihydro-3H- pyrazino[1,2- c]pyrimidine-1,6,8-trione::US10011607, 43

SMILES C[C@@]12CC(=O)N(C(=O)N1CCN(C2=O)c1cnc(OC2CC2)nc1)c1c(F)cc(cc1F)C#Cc1ccccc1

InChI Key InChIKey=GNJWLMMWHACAHX-LJAQVGFWSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402213   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM402213((9aS)-2-[2-(cyclopro- poxy)pyrimidin- 5-yl]-7-[2,6...)
Affinity DataEC50:  171nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent