BDBM402321 6-(3-(2-chloro-4-((5- cyclopropyl-3-(2,6- dichlorophenyl)isoxazol-4- yl)methoxy)phenyl)-3- hydroxyazetidin-1- yl)nicotinic acid::US10329286, Example 2::US11247986, Example 2
SMILES OC1(CN(C1)c1ccc(OC=O)cn1)c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C2CC2)cc1Cl
InChI Key InChIKey=LFVWDVUXUDKRGB-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 402321
Affinity DataEC50: 2.60nMAssay Description:Expression and purification of the FXR-LBD: An overnight preculture of a transformed E. coli strain was diluted 1:20 in LB-Ampicillin medium and grow...More data for this Ligand-Target Pair
Affinity DataEC50: 2.60nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR was performed as follow...More data for this Ligand-Target Pair