BDBM402392 US10329282, Compound TDI01344-2A::US11390609, Compound TDI01344-2A

SMILES CN(C(CO)CO)C(=O)c1cc2ccc(cc2[nH]1)-c1nccc(Nc2ccc(cc2)-c2cn[nH]c2)n1

InChI Key InChIKey=QKMPSZSQUHVLAZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 402392   

TargetRho-associated protein kinase 2 [1-119](Homo sapiens (Human))
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM402392(US10329282, Compound TDI01344-2A | US11390609, Com...)
Affinity DataIC50:  107nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM402392(US10329282, Compound TDI01344-2A | US11390609, Com...)
Affinity DataIC50:  107nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM402392(US10329282, Compound TDI01344-2A | US11390609, Com...)
Affinity DataIC50:  4.21E+3nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent