BDBM402400 US10329282, Compound TDI01424::US11390609, Compound TDI01424

SMILES O=C(NC1CCC1)c1cc2ccc(cc2[nH]1)-c1nc(Nc2ccc(cc2)-c2cn[nH]c2)c2sccc2n1

InChI Key InChIKey=IFJYHSKTOJVFED-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 402400   

TargetRho-associated protein kinase 2 [1-119](Homo sapiens (Human))
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM402400(US10329282, Compound TDI01424 | US11390609, Compou...)
Affinity DataIC50:  138nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM402400(US10329282, Compound TDI01424 | US11390609, Compou...)
Affinity DataIC50:  138nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM402400(US10329282, Compound TDI01424 | US11390609, Compou...)
Affinity DataIC50:  4.98E+3nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent