BDBM402428 US10329291, Example 19

SMILES COc1cnc2c(Nc3ccc(F)c(c3)[C@]34CCC[C@H]3S(=O)(=O)N(C)C(=N)N4)nccc2c1

InChI Key InChIKey=ANSVHMJEANLWCE-XMSQKQJNSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 402428   

TargetBeta-secretase 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM402428(US10329291, Example 19)
Affinity DataKi:  10nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM402428(US10329291, Example 19)
Affinity DataKi:  31nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent