BDBM402740 N-(3-cyano-1-methyl-1H- pyrazol-4-yl)-2-[(1S,4S)- or (1R,4R)-2,5- diazabicyclo[2.2.2]oct-2- yl]pyrrolo[2,1- f][1,2,4]triazine-7- carboxamide trifluoroacetate::US10329295, Example 47
SMILES Cn1cc(NC(=O)c2ccc3cnc(nn23)N2C[C@H]3CC[C@@H]2CN3)c(n1)C#N
InChI Key InChIKey=OPXFFQQCPSTNPD-VXGBXAGGSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 402740
Affinity DataIC50: 265nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair