BDBM402792 2-[(1S,5S)- or (1R,5R)-3,6- diazabicyclo[3.2.1]oct-3- yl]-N-[1-methyl-3- (trifluoromethyl)-1H- pyrazol-4-yl]pyrrolo[2,1- f][1,2,4]triazine-7- carboxamide::US10329295, Example 100

SMILES Cn1cc(NC(=O)c2ccc3cnc(nn23)N2C[C@@H]3CN[C@@H](C3)C2)c(n1)C(F)(F)F

InChI Key InChIKey=OGXDDAVKGVTLEM-QWRGUYRKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402792   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402792(2-[(1S,5S)- or (1R,5R)-3,6- diazabicyclo[3.2.1]oct...)
Affinity DataIC50:  64nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent