BDBM402811 2-[(3S)-3-aminopiperidin- 1-yl]-N-(3-cyano-1- methyl-1H-pyrazol-4- yl)pyrrolo[2,1- f][1,2,4]triazine-7- carboxamide trifluoroacetate::US10329295, Example 123

SMILES Cn1cc(NC(=O)c2ccc3cnc(nn23)N2CCC[C@H](N)C2)c(n1)C#N

InChI Key InChIKey=MGIYGLLUGFDVFB-NSHDSACASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402811   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402811(2-[(3S)-3-aminopiperidin- 1-yl]-N-(3-cyano-1- meth...)
Affinity DataIC50:  1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent