BDBM403331 US10329320, Compound 8
SMILES COC[C@]12CC[C@@](C)(O)C[C@@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)Cn4nc5ccc(F)c(F)c5n4)[C@@]3(C)CC[C@H]21
InChI Key InChIKey=KOXFAJCPBYWCJO-DTZLGSCESA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 403331
TargetGamma-aminobutyric acid (GABA) B receptor 1(Rattus norvegicus (rat))
Sage Therapeutics
US Patent
Sage Therapeutics
US Patent
Affinity DataIC50: <10nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair