BDBM403361 US10329320, Compound 42::US10329320, Compound 48::US11124538, Compound 48

SMILES COC[C@]12CC[C@@](C)(O)C[C@@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)Cn4cc5ccc(OC)cc5n4)[C@@]3(C)CC[C@H]21

InChI Key InChIKey=RZMHOAZWKIGEAQ-ALGWOHKESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 403361   

TargetGamma-aminobutyric acid (GABA) B receptor 1(Rattus norvegicus (rat))
Sage Therapeutics

US Patent
LigandPNGBDBM403361(US10329320, Compound 42 | US10329320, Compound 48 ...)
Affinity DataIC50:  30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid (GABA) B receptor 1(Rattus norvegicus (rat))
Sage Therapeutics

US Patent
LigandPNGBDBM403361(US10329320, Compound 42 | US10329320, Compound 48 ...)
Affinity DataIC50:  75nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid (GABA) B receptor 1(Rattus norvegicus (rat))
Sage Therapeutics

US Patent
LigandPNGBDBM403361(US10329320, Compound 42 | US10329320, Compound 48 ...)
Affinity DataIC50:  75nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent