BDBM403365 US10329320, Compound 46
SMILES COC[C@]12CC[C@@](C)(O)C[C@@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)Cn4cc5ccncc5n4)[C@@]3(C)CC[C@H]21
InChI Key InChIKey=ZZHBHKZIQGYADB-ADAKBSHOSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 403365
TargetGamma-aminobutyric acid (GABA) B receptor 1(Rattus norvegicus (rat))
Sage Therapeutics
US Patent
Sage Therapeutics
US Patent
Affinity DataIC50: 30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair