BDBM403669 (3aR,7S,10S,11S,12R)-1-acetyl-7-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-16-methoxy-11-methyl-5,8-dioxo-1,2,3,3a,5,6,7,8,11,12,20,21,22,23,24,24a-hexadecahydro-10H-9,12-methanopyrrolo[2′,3′:18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-10-carboxamide::US10335409, Example 80
SMILES COc1ccc2nc(Cl)c(O[C@H]3CN([C@@H]([C@@H]3C)C(=O)OC(C)(C)C)C(=O)[C@@H](NC(=O)O[C@@H]3CCN([C@H]3CCCC=C)C(C)=O)C(C)(C)C)nc2c1
InChI Key InChIKey=YZMVHBZUAKOBBJ-YEIJCASKSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 403669
Affinity DataKi: 0.490nMAssay Description:Purified NS3 protease domain (amino acids 1-181) of the genotype 1b and 3a virus were generated as above. The internally quenched fluorogenic depsipe...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 3a (isolate k3a) (HCV))
Gilead Pharmasset
US Patent
Gilead Pharmasset
US Patent
Affinity DataKi: 13nMAssay Description:Purified NS3 protease domain (amino acids 1-181) of the genotype 1b and 3a virus were generated as above. The internally quenched fluorogenic depsipe...More data for this Ligand-Target Pair