BDBM404054 (2S,5R)-1-(4-(2-chloro-4-methoxypyrimidin-5-yl)benzoyl)-5-(2-chlorophenyl)pyrrolidine-2-carboxylic acid::US10017468, Compound 283::US10781171, Compound 283::US11072582, Compound 283
SMILES COc1nc(Cl)ncc1-c1ccc(cc1)C(=O)N1[C@@H](CC[C@@H]1c1ccccc1Cl)C(O)=O
InChI Key InChIKey=AICDWVMPBOYWLH-MOPGFXCFSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 404054
Affinity DataEC50: <200nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
Affinity DataEC50: <200nMAssay Description:The assay was used to determine the activity of the compounds of the invention. The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM ...More data for this Ligand-Target Pair
Affinity DataEC50: <200nMAssay Description:The assay was used to determine the activity of the compounds of the invention.The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM N...More data for this Ligand-Target Pair
Affinity DataEC50: <200nMAssay Description:The following assay can be used for determination of GPR43 activation. When a GPCR is in its active state, either as a result of ligand binding or co...More data for this Ligand-Target Pair