BDBM404382 (R)-N-(1-cyanopyrrolidin-3-yl)- [1,1'-biphenyl]-4-carboxamide::US10343992, Example 35::US10689345, Example 35::US11066365, Example 35::US11390584, Example 35

SMILES O=C(N[C@@H]1CCN(C1)C#N)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=CCMLFCPHJPWXFB-QGZVFWFLSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 404382   

TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Missions Therapeutics

US Patent
LigandPNGBDBM404382((R)-N-(1-cyanopyrrolidin-3-yl)- [1,1'-biphenyl]-4-...)
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Missions Therapeutics

US Patent
LigandPNGBDBM404382((R)-N-(1-cyanopyrrolidin-3-yl)- [1,1'-biphenyl]-4-...)
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Missions Therapeutics

US Patent
LigandPNGBDBM404382((R)-N-(1-cyanopyrrolidin-3-yl)- [1,1'-biphenyl]-4-...)
Affinity DataIC50: <100nMAssay Description:USP30 biochemical fluorescence intensity IC50 assay Dilution plates were prepared at 21 times the final concentration (2100 μM for a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Missions Therapeutics

US Patent
LigandPNGBDBM404382((R)-N-(1-cyanopyrrolidin-3-yl)- [1,1'-biphenyl]-4-...)
Affinity DataIC50: <100nMAssay Description:USP30 Biochemical Fluorescence Intensity Kinetic Assay.Reactions were performed in duplicate in black 384 well plates (small volume, Greiner 784076) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent