BDBM404823 N-methyl-1-(4-{6-[2-(pyridin-2- yl)acetamido]pyridazin-3-yl}butyl)- 1H-1,2,3-triazole-4-carboxamide::US10344025, Example 167::US11370786, Example 167
SMILES CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3ccccn3)nn2)nn1
InChI Key InChIKey=CXJJWABOFJIHGQ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 404823
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
The University Of Texas System
US Patent
The University Of Texas System
US Patent
Affinity DataIC50: <100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
The University Of Texas System
US Patent
The University Of Texas System
US Patent
Affinity DataIC50: <100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
The University Of Texas System
US Patent
The University Of Texas System
US Patent
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair