BDBM406064 1-(1',4-dimethyl- 1-phenyl-1H,1'H- 3,4'-bipyrazol-5- yl)-3-(3-(2,2,2- trifluoroethyl)- 2,3,4,5- tetrahydro-1H- benzo[d]azepin- 1-yl)urea::US10351575, Example 18::US10889589, EX. # 18

SMILES Cc1c(NC(=O)NC2CN(CC(F)(F)F)CCc3ccccc23)n(nc1-c1cnn(C)c1)-c1ccccc1

InChI Key InChIKey=OLGOUBARXHVBAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 406064   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM406064(1-(1',4-dimethyl- 1-phenyl-1H,1'H- 3,4'-bipyrazol-...)
Affinity DataIC50:  550nMAssay Description:TrkA binding activity was determined in a TrkA LanthaScreen™ Eu Kinase Binding Assay. 5 nM His-tagged recombinant human TrkA (6HIS tagged cytoplasmic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM406064(1-(1',4-dimethyl- 1-phenyl-1H,1'H- 3,4'-bipyrazol-...)
Affinity DataIC50:  550nMAssay Description:TrkA binding activity was determined in a TrkA LanthaScreen™ Eu Kinase Binding Assay. 5 nM His-tagged recombinant human TrkA (6HIS tagged cytoplasmic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent