BDBM406128 US10351575, Example 80::US10889589, EX. # 80

SMILES Cc1c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)n(nc1-c1cnn(C)c1)-c1ccccc1

InChI Key InChIKey=GRACNZQVICFVBL-ISKFKSNPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 406128   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM406128(US10351575, Example 80 | US10889589, EX. # 80)
Affinity DataIC50: <100nMAssay Description:TrkA binding activity was determined in a TrkA LanthaScreen™ Eu Kinase Binding Assay. 5 nM His-tagged recombinant human TrkA (6HIS tagged cytoplasmic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM406128(US10351575, Example 80 | US10889589, EX. # 80)
Affinity DataIC50: <100nMAssay Description:TrkA binding activity was determined in a TrkA LanthaScreen™ Eu Kinase Binding Assay. 5 nM His-tagged recombinant human TrkA (6HIS tagged cytoplasmic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent