BDBM406153 (S)-1-(1',4-dimethyl-1- phenyl-1H,1'H-[3,4'- bipyrazol]-5-yl)-3-(6- fluoro-1,2,3,4- tetrahydronaphthalen-1- yl)urea::US10351575, Example 103::US10889589, EX. # 103

SMILES Cc1c(NC(=O)N[C@H]2CCCc3cc(F)ccc23)n(nc1-c1cnn(C)c1)-c1ccccc1

InChI Key InChIKey=DXHYJYDQWUIWTA-QFIPXVFZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 406153   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM406153((S)-1-(1',4-dimethyl-1- phenyl-1H,1'H-[3,4'- bipyr...)
Affinity DataIC50: <100nMAssay Description:TrkA binding activity was determined in a TrkA LanthaScreen™ Eu Kinase Binding Assay. 5 nM His-tagged recombinant human TrkA (6HIS tagged cytoplasmic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM406153((S)-1-(1',4-dimethyl-1- phenyl-1H,1'H-[3,4'- bipyr...)
Affinity DataIC50: <100nMAssay Description:TrkA binding activity was determined in a TrkA LanthaScreen™ Eu Kinase Binding Assay. 5 nM His-tagged recombinant human TrkA (6HIS tagged cytoplasmic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent