BDBM406453 6-butyl-5-(2,6- dimethoxyphenyl)- 3-{5-[(2-phenyl- 1,3-thiazol-4- yl)methyl]-1,3,4- oxadiazol-2- yl}pyridine-2,4-diol::US10336739, Example 46

SMILES CCCCc1nc(O)c(-c2nnc(Cc3csc(n3)-c3ccccc3)o2)c(O)c1-c1c(OC)cccc1OC

InChI Key InChIKey=QAEBIAFZVSGLHH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406453   

TargetApelin receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM406453(6-butyl-5-(2,6- dimethoxyphenyl)- 3-{5-[(2-phenyl-...)
Affinity DataEC50:  5.5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent