BDBM406834 N-{4-[(5-{[(2-hydroxy-2-methylpropyl)amino]methyl}-2-(pyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl)amino]pyridin-2-yl}acetamide::US10336761, Example 117
SMILES CC(=O)Nc1cc(Nc2nc(nn3ccc(CNCC(C)(C)O)c23)-c2ccccn2)ccn1
InChI Key InChIKey=WIBYDWSNIHNEPL-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 406834
Affinity DataIC50: 340nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair