BDBM407808 (R)-methyl 3-((2-(3-cyano- pyrrolo[1,2-b]pyridazin-7- yl)-5-(((R)-2-fluoro-3- hydroxy-3-methylbutyl) carbamoyl)pyridin-4- yl)amino)pyrrolidine-1- carboxylate::US10336762, Compound 752
SMILES COC(=O)N1CC[C@H](C1)Nc1cc(ncc1C(=O)NC[C@@H](F)C(C)(C)O)-c1ccc2cc(cnn12)C#N
InChI Key InChIKey=GUJSUURNRWCKEQ-OPAMFIHVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 407808
Affinity DataIC50: <1nMAssay Description:Cryopreserved human monocytes (Stem Cell Technologies) were thawed, diluted in RPMI with GlutaMAX (GibcoŽ 200 mM L-alanyl-L-glutamine) (10 mM HEPES, ...More data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Cryopreserved human monocytes (Stem Cell Technologies) were thawed, diluted in RPMI with GlutaMAX (GibcoŽ 200 mM L-alanyl-L-glutamine) (10 mM HEPES, ...More data for this Ligand-Target Pair