BDBM408050 US10336774, Example 17a

SMILES N[C@H]1CCC11CCN(CC1)c1cnc(c(N)n1)-c1cccc(Cl)c1Cl

InChI Key InChIKey=UVVZJMVSBWFQEI-ZDUSSCGKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408050   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM408050(US10336774, Example 17a)
Affinity DataIC50:  120nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent