BDBM408091 US10336774, Example 86a
SMILES C[C@H]1CCC2(CCN(CC2)c2cnc(Sc3cccnc3C(F)(F)F)c(N)n2)[C@@H]1N
InChI Key InChIKey=JEKOLHGTVUGXHG-SWLSCSKDSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 408091
Affinity DataIC50: 10nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair