BDBM408091 US10336774, Example 86a

SMILES C[C@H]1CCC2(CCN(CC2)c2cnc(Sc3cccnc3C(F)(F)F)c(N)n2)[C@@H]1N

InChI Key InChIKey=JEKOLHGTVUGXHG-SWLSCSKDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408091   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM408091(US10336774, Example 86a)
Affinity DataIC50:  10nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent