BDBM408120 4-(4-(1-(Benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-1-yl)-6-chloropyrimidine::US10336775, Example 24::US11046712, No 24

SMILES CC(N1CCN(CC1)c1cc(Cl)ncn1)c1ccc2OCOc2c1

InChI Key InChIKey=YETOTNSLBAWPQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408120   

TargetProtein O-GlcNAcase(Homo sapiens (Human))
Asceneuron

US Patent
LigandPNGBDBM408120(4-(4-(1-(Benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-...)
Affinity DataIC50:  125nMAssay Description:5 μI of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Asceneuron

US Patent
LigandPNGBDBM408120(4-(4-(1-(Benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-...)
Affinity DataIC50:  125nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent