BDBM408332 5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(3-(trifluoromethyl)phenyl) cyclopropyl) pyrimidin-2-amine ::US10357493, Example 49

SMILES FC(F)c1nnc(o1)-c1cnc(NC2(CC2)c2cccc(c2)C(F)(F)F)nc1

InChI Key InChIKey=JUEKLLPPPOBEDZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408332   

TargetHistone deacetylase 1(Homo sapiens (Human))
Selenity Therapeutics (Bermuda)

US Patent
LigandPNGBDBM408332(5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...)
Affinity DataIC50: >3.00E+4nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Selenity Therapeutics (Bermuda)

US Patent
LigandPNGBDBM408332(5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...)
Affinity DataIC50:  16nMAssay Description:All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent