BDBM408496 1-(2-fluoro-4- (trifluoromethyl) phenyl)propan-1-ol::US10358435, Example 17

SMILES CCC(O)c1ccc(cc1F)C(F)(F)F

InChI Key InChIKey=CUGQSKPXUJRTGT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408496   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM408496(1-(2-fluoro-4- (trifluoromethyl) phenyl)propan-1-o...)
Affinity DataKi:  36.2nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM408496(1-(2-fluoro-4- (trifluoromethyl) phenyl)propan-1-o...)
Affinity DataKi:  44.7nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent