BDBM408547 (R)- or (S)-6-(5-(1-(2- fluoro-4-(trifluoromethyl)- phenyl)ethyl)-4-methyl-4H- 1,2,4-triazol-3-yl)-2- methylpyrimidin-4(3H)-one::US10358435, Example 63::US10358435, Example 64
SMILES CC(c1nnc(-c2cc(=O)[nH]c(C)n2)n1C)c1ccc(cc1F)C(F)(F)F
InChI Key
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 408547
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 16nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 23.3nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair