BDBM408575 (S)- or (R)-6-(7-(2-Fluoro-4- (trifluoromethyl)phenyl)-7- methyl-4,5,6,7-tetrahydro- [1,2,3]triazolo[1,5-a]pyridin-3- yl)-2-(3-methoxy- benzyl)pyrimidin-4(3H)-one::US10358435, Example 91::US10358435, Example 92
SMILES COc1cccc(Cc2nc(cc(=O)[nH]2)-c2nnn3c2CCCC3(C)c2ccc(cc2F)C(F)(F)F)c1
InChI Key
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 408575
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.560nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 728nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair