BDBM408629 1-((3r,5r,7r)-adamantan-1-yl)-2-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)ethanol::US10358451, Compound 15e
SMILES Fc1cccc2-c3cncn3C(CC(=O)C34CC5CC(CC(C5)C3)C4)c12
InChI Key InChIKey=BQEDTZNVILXUMB-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 408629
Affinity DataIC50: <500nMAssay Description:In vitro TDO enzymatic activity was determined in a mixture of 50 mM potassium phosphate buffer, pH 6.5; 200 nM human TDO enzyme, 300 μM L-Trypt...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair