BDBM408911 Methyl 1-(N-((3'-chloro-4'-(trifluoromethoxy)- [1,1'-biphenyl]-4-yl)methyl)-3,3- dimethylbutanamido) isoquinoline-6-carboxylate::US10377717, Compound 41

SMILES COC(=O)c1ccc2c(nccc2c1)N(Cc1ccc(cc1)-c1ccc(OC(F)(F)F)c(Cl)c1)C(=O)CC(C)(C)C

InChI Key InChIKey=KEVIVJVLSJRBJW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408911   

TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408911(Methyl 1-(N-((3'-chloro-4'-(trifluoromethoxy)- [1,...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent