BDBM409510 N,N-Dimethyl-2-[6-(3,4,5-trifluorophenyl)pyrrolo[3,2-b]pyridin-1-::US10377753, Example 375

SMILES CN(C)C(=O)Cn1ccc2ncc(cc12)-c1cc(F)c(F)c(F)c1

InChI Key InChIKey=MWLOPKQSTYQGEH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 409510   

TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409510(N,N-Dimethyl-2-[6-(3,4,5-trifluorophenyl)pyrrolo[3...)
Affinity DataIC50:  12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent