BDBM410011 US10370339, Example 2-18

SMILES COC(=O)Cc1cc2nc(Nc3ccc(OC(C)C)cc3)n([C@@H]3C[C@H](C)CC[C@H]3C(C)C)c2cc1OC

InChI Key InChIKey=DVXUMPBNIYZYKT-UGIARPQZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 410011   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM410011(US10370339, Example 2-18)
Affinity DataIC50:  120nMAssay Description:Mutant IDH1 R132H Biochemical Assay mIDH1 catalyzes the NADPH-dependent reduction of alpha-ketoglutarate (a-KG) to (2R)-2-hydroxyglutarate (2-HG). NA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent