BDBM410099 US10370370, Compound 3-P1

SMILES Clc1ccc2c(NC3CN4CCC3CC4)noc2c1

InChI Key InChIKey=WLVXTRCIWADVNT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 410099   

Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Axovant Sciences

US Patent
LigandPNGBDBM410099(US10370370, Compound 3-P1)
Affinity DataKi:  32nMAssay Description:h-5HT3: In brief, Chinese Hamster Ovary (CHO) cells stably expressing human 5-HT3 serotonin receptors, grown to confluence in 175 cm2 flasks. Followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences

US Patent
LigandPNGBDBM410099(US10370370, Compound 3-P1)
Affinity DataKi:  1.40E+3nMAssay Description:α7 nAChR: The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent