BDBM410188 5-((2R,4S)-4-cyano-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile ::US10370379, Compound 5::US11059827, Compound 5
SMILES Fc1ccc(F)c(c1)[C@H]1C[C@@H](CN1c1ccn2ncc(C#N)c2n1)C#N
InChI Key InChIKey=GUHRRWWDOFQWKH-BDJLRTHQSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 410188
Affinity DataIC50: 300nMAssay Description:In each well of a 384-well plate, 1 nM-1.5 nM of wild type NTRK1 enzyme (BPS Bioscience; 40280) was incubated in a total of 12.5 μL of buffer (1...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:In each well of a 384-well plate, 1 nM-1.5 nM of wild type NTRK1 enzyme (BPS Bioscience; 40280) was incubated in a total of 12.5 μL of buffer (1...More data for this Ligand-Target Pair